Azathioprine for Crohns/Colitis

Azathioprine for Crohns/Colitis

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nail_it

Original Poster:

968 posts

208 months

Thursday 27th November 2014
quotequote all
Interested to hear from anyone taking Azathioprine and their results.
Just started on it as spent too much time now on Prednisolone and suffering it's side affects.

SomersetWestie

402 posts

180 months

Thursday 27th November 2014
quotequote all
Been on it for 25 years to control the Crohns, and generally it works for me !! Keeps me off the Prednisolone, which is always a bonus. No real side effects, none that i could differentiate over Crohn's side effects anyway !

4 years ago the consultant decided to stop them, and said it would be a few months before i'd notice any difference, which she didn't think i would. I duly did of course, the Crohn's relapsed and i ended up having surgery. Needless to say, I've been back on them for 3 years and everything going well :-)

dumfriesdave

384 posts

137 months

Thursday 27th November 2014
quotequote all
Been on Aza for over 2 years now and honestly don't find a massive improvement.
However I am on a very small dose (only 50mg).
The constant blood tests at the beginning were a nuisance, but very important due to the amount of side effects.

I still get regular flare-ups even though Aza is supposed to prevent them.
Still feel a bit sickly and poorly after taking them - gives an ideal excuse for an afternoon nap.

nail_it

Original Poster:

968 posts

208 months

Friday 28th November 2014
quotequote all
Useful and interesting reading. Many thanks for responding.
Started on 50mgs of Aza on Tuesday increasing to 100mgs twice daily next Tuesday. Plus all the blood tests which is not a prob as I seem to have so many particularly when I've been in hospital on i.v.steriods.
Still having to continue on 30mgs on Prednisolone, tapering off weekly
Fingers x'd I tolerate it and no more Prednisolone. It seriously affects my weight plus all the other side affects!

Rib

2,548 posts

189 months

Saturday 29th November 2014
quotequote all
It's generally one of the 1st drugs they put you on, pretty low risk and few side effects. If it works for you then much better than pred!

Something else to consider is modulan, supplement feed (or you can go the whole hog and do nil by mouth diet) didn't work when I was younger and my crohns was very aggressive causing strictures which obviously nothing but surgery could sort, but worked a treat after all the other drugs stopped working. It has natural anti inflammatorys and is specifically designed for crohns.