Difficulty getting pregnant....

Difficulty getting pregnant....

Author
Discussion

Lotus82

82 posts

131 months

Tuesday 20th May 2014
quotequote all
Super Slo Mo said:
Unfortunately, as the wife is 35, she's too old for any NHS funding apparently, much to the surprise of the private clinic we went to yesterday.

She's putting a brave face on it, but is unhappy, yesterday's initial scan didn't elicit a 'positive' response from the person carrying it out (although they haven't said why yet), and now she's worrying.

I've tried to stop her googling all the possible complications as she's getting worked up.

Telling her that nothing will change, worse case is that we carry on as we are, isn't exactly helping either, although it's the truth. Suggestions of a puppy, kitten or motorbike aren't cheering her up as much as they normally would either smile
Super Slo Mo. You'll find this thread most helpful. I certainly have. Plenty of knowledgeable people on here from trained professionals to people who have been there and got the T-shirt.

At 35 your wife most certainly does qualify for NHS funding (click for link - read 'Women under 40' paragraph). Who told you you were not qualified? You GP?

From my experience the GP's we saw were not helpful, it was only when we got referred to a fertility specialist that things started moving.

Your wife's urge to research the matter is natural, however it will not help either of you.

Home truth's such as 'we'll be ok together' and 'lets get a puppy' are not helpful, especially at this early stage. If it is something you both want you should focus on doing what you can; drink less, eat healthy, get plenty of exercise, holiday, etc. Get your bodies healthy both physically and mentally.

The road ahead can be long and you will need to be positive and help each other when a tough day comes along.

Lotus82

82 posts

131 months

Tuesday 20th May 2014
quotequote all
Update from me:

In summary; we're pregnant following frozen embryo transfer. Two embryos transferred, first IVF scan soon where we will find out if both embryos made it. Exciting.

We've had our usual issues:
- Admin error post transfer showed we had another couple's implantation paper work. Hospital were incredibly apologetic as this caused 12 hours of stress while theiy figured out if they did/did not put the wrong embryos in my wife!
- Late night trip to the hospital following a bleed. After an exam all signs were positive and sent home.
- Wife suffered pretty epic morning sickness this weekend. Could not keep down sips of water let alone food. This continued for 2 days before some travel wrist bands solved the problem, she quickly re-hydrated and normal service was resumed.

Fingers tightly crossed the next few weeks pass without issue.

Thank you for all the support, advice and knowledge. It was a great help.

Super Slo Mo

5,368 posts

198 months

Tuesday 20th May 2014
quotequote all
Lotus82 said:
Super Slo Mo. You'll find this thread most helpful. I certainly have. Plenty of knowledgeable people on here from trained professionals to people who have been there and got the T-shirt.

At 35 your wife most certainly does qualify for NHS funding (click for link - read 'Women under 40' paragraph). Who told you you were not qualified? You GP?

From my experience the GP's we saw were not helpful, it was only when we got referred to a fertility specialist that things started moving.

Your wife's urge to research the matter is natural, however it will not help either of you.

Home truth's such as 'we'll be ok together' and 'lets get a puppy' are not helpful, especially at this early stage. If it is something you both want you should focus on doing what you can; drink less, eat healthy, get plenty of exercise, holiday, etc. Get your bodies healthy both physically and mentally.

The road ahead can be long and you will need to be positive and help each other when a tough day comes along.
I know it's not what most would perceive as helpful, but it's our standard sort of humour, she knows I'm just trying to lift her spirits. We've spent 18 years taking the piss out of each other gently, that's all it is.

Our NHS region is the only one in the country that has a hard stop at 34 and a half years, apparently. The clinic we went to yesterday described the documents we have from the NHS saying no as 'brutal'. We are trying to appeal, but don't hold out much hope.

We've both gone down the health improvement route, I've lost nearly 2 stones, we're both fitter (me considerably more so), neither drink now. She has a stressful job, I don't particularly, other than when I'm spending weeks away in a stinky, dirty, dangerous sthole, but I try not to let it bother me.

We're a bit in limbo for a couple of weeks now, I have an SFA in two weeks, then we both go back for another meeting, no doubt where they tell us what they can or can't do next.

Legend83

Original Poster:

9,960 posts

222 months

Tuesday 20th May 2014
quotequote all
Lotus82 said:
Update from me:

In summary; we're pregnant following frozen embryo transfer. Two embryos transferred, first IVF scan soon where we will find out if both embryos made it. Exciting.

We've had our usual issues:
- Admin error post transfer showed we had another couple's implantation paper work. Hospital were incredibly apologetic as this caused 12 hours of stress while theiy figured out if they did/did not put the wrong embryos in my wife!
- Late night trip to the hospital following a bleed. After an exam all signs were positive and sent home.
- Wife suffered pretty epic morning sickness this weekend. Could not keep down sips of water let alone food. This continued for 2 days before some travel wrist bands solved the problem, she quickly re-hydrated and normal service was resumed.

Fingers tightly crossed the next few weeks pass without issue.

Thank you for all the support, advice and knowledge. It was a great help.
beer

Lotus82

82 posts

131 months

Monday 2nd June 2014
quotequote all
How's it going Super Slo Mo?

Hope all is well.

Super Slo Mo

5,368 posts

198 months

Monday 2nd June 2014
quotequote all
Slow, appropriately enough wink, thanks for asking though.

I've been for my SFA today, then we go back on Friday for the results of both our tests. I now know that the OH has fibroids, which she didn't tell me initially; that's not concerning her too much, it's what the consultant didn't tell her that got her worrying a bit on the first day or so after the scans.

Having said that, it only took her a day or two to get back to her usual happy self, we've had a chat about the alternatives if we are faced with the worse case scenario. We're both fairly philosophical about the whole thing, whatever will be, will be, as they say. It's easy to say that now though, might not be after we know for sure.

What's a bit frustrating for me is that I have to go away for a month or so at the weekend, I'm not looking forward to it, although that's just because I don't want to go as much as anything else.

Lotus82

82 posts

131 months

Tuesday 3rd June 2014
quotequote all
Super Slo Mo said:
Slow, appropriately enough wink, thanks for asking though.

I've been for my SFA today, then we go back on Friday for the results of both our tests. I now know that the OH has fibroids, which she didn't tell me initially; that's not concerning her too much, it's what the consultant didn't tell her that got her worrying a bit on the first day or so after the scans.

Having said that, it only took her a day or two to get back to her usual happy self, we've had a chat about the alternatives if we are faced with the worse case scenario. We're both fairly philosophical about the whole thing, whatever will be, will be, as they say. It's easy to say that now though, might not be after we know for sure.

What's a bit frustrating for me is that I have to go away for a month or so at the weekend, I'm not looking forward to it, although that's just because I don't want to go as much as anything else.
I found the worrying from Mrs Lotus82 got rather full on, especially when she considered what a doctor or consultant could/could not have mentioned. Great to hear she was able to pick her self back up and find some balance again.

What ever Friday's outcome it will take time to absorb the news. Stay positive, let us know how you got on.

Good luck with the travel. I'm abroad a great deal with work, however, my trips are never more than a week and they can be brutal, I fully sympathies with you having to go away for a month.

Super Slo Mo

5,368 posts

198 months

Tuesday 3rd June 2014
quotequote all
Cheers

It's unusual that I have to go away for such a long time, but this year it's the second month long stint I've got to do. No other biggies in the pipeline after this, fortunately. I'm at the stage now where I'm sick of the travelling, or at least, the being away, I've done it for so long that it's certainly no novelty.

Anyway, fingers crossed we'll have something positive to take away on Friday.

Super Slo Mo

5,368 posts

198 months

Thursday 12th June 2014
quotequote all
Quick update.

Despite having a reasonably normal sperm count, less than 1% are 'normal', so apparently it's highly unlikely that we can achieve pregnancy the normal way.
Even Ivf would not necessarily be successful apparently, we need to have the icsi procedure. Nice and expensive.
We won't be doing it any time soon as the missus needs to have an operation (fibroids) before the consultant will let us proceed.

Not much else to say really, just a long period of limbo while we wait.

h0b0

7,577 posts

196 months

Friday 13th June 2014
quotequote all
Super Slo Mo said:
Quick update.

Despite having a reasonably normal sperm count, less than 1% are 'normal', so apparently it's highly unlikely that we can achieve pregnancy the normal way.
Even Ivf would not necessarily be successful apparently, we need to have the icsi procedure. Nice and expensive.
We won't be doing it any time soon as the missus needs to have an operation (fibroids) before the consultant will let us proceed.

Not much else to say really, just a long period of limbo while we wait.
While the fibroids operation can be mentally traumatic the actual procedure is nothing to be concerned about. With all of this just see it as another "success" and step closer to being pregnant once she has gone through it. Then you can celebrate the hurdles instead of being negative.

Your sperm numbers are very similar to where mine were in 2012. You are probably going to read a crap load of information on the internet to see if you can "fix" it. There is so much conflicting information that you will drive yourself crazy. The first thing to know is that alcohol is almost certainly not a factor. It will only be one if you are taking a swig of vodka to get you out of bed in the morning. If you are, can I ask you to reconsider having kids?

The most important fact about sperm quality is that it takes 3 months for any change to have an impact. You can have a common, and easily fixable, prostate infection that will change the morphology (appearance) and make the sperm unable to penetrate the egg. Clear this up and wait 3 months to see if there is an improvement. In my case I had the infection but also when we looked back 3 months from my first test we realized that it was when I was very sick. Being ill will have an impact on quality and in my case it did. But, we decided not to wait and see just in case there was another issue (which there was)

So, we did icsi.

Here are a couple of posts I made in 2011 that may help to explain the process. And some good news, both my wife and I had issues that would 100% prevent pregnancy. We now have 2 kids through ICSI. So even when you and your wife are feeling low they and bounce back with that knowledge.


h0b0 said:
In IVF the ovaries are stimulated to make many more follicles containing eggs than they would normally. This is done by injection of drugs just under the skin. Small needle and no pain. The ovaries do swell and she may look like she is on her period or even pregnant. This can be uncomfortable. She will be monitored constantly and the drug dosage will be adapted to how she responds. If she is over stimulated they will cancel the IVF round as it can cause issues.

The actual harvesting requires a needle in the arse muscle to trigger the ovaries. The needle is a decent size so when you do it, just bloody do it. Do not hesitate as it most likely will not hurt. A few hours later (can't recall how many might be 36)they will place your wife/girlfriend under general anesthetic and remove the follicles. The removal is not uncomfortable but she will be groggy from the anesthetic. (some places do this under local as it is not painful)

3 to 5 days later depending on how the eggs fertilize and grow they will be put back in. This is no worse than a Pap smear and afterwards she will not be allowed to stand for 30 minutes and that is it. It feels very strange walking out as you are convinced they will fall out.

During the entire IVF her progesterone levels will be monitored and adjusted using an injection in the arse muscle. Again it looks quite a long needle but just stab it in and get it done. In my wife's case she preferred the needle to the suppository progesterone as the needle is over and done quickly and the suppository is messy.

IVF is a challenge and all the injections can be overwhelming. Try to break it down into manageable chunks and try not to listen to the doom sayers that would have you believe it is hell.

My wife is 6 months pregnant as a result of first round ICIS IVF. We have had a load of other issues which meant IVF was "easy" in comparison. We made a point of living life while doing IVF so went on a couple of holidays and just did the injections in the hotel. Having said all that the way my wife has dealt with everything has left me in no doubt about her strength.
h0b0 said:
ICSI is just a small part of the overall IVF process.
For ICSI they select a sperm and insert it by needle into the egg.



This is because the genetic make up of your sperm is almost certainly good but he may have a funky looking head which will not allow him into the egg.

The eggs are then left to fertilize and monitored. On the morning of the third day they will take a look at the number of cells that have formed. Ideally they want 8 cells and no fragmentation. If they see this they may wait until the 5th day before putting them back in. This gives them more time to observe the progress. Normally, they will see less cells and some fragmentation so they will decide if they are going to wait for the 5th day or not.

This egg is perfect with 8 cells,



This egg would have little chance of success,



However, this one is perfect in my eyes and will be called Liam in 3 months



here you can see 5 clear cells and then some smaller fragments

Few things on egg quality,

A high or low number harvest/extracted does not directly link to quality. We had 14 eggs of which 12 fertilized and 3 made it to day 3 with no expectation of any making it to day 5. None stored 2 put in and one taking hold. These are low results from the initial number that came out and can go some way to explaining our issues. So if you only have two come out do not panic they may be two excellent ones. Also, if your eggs are not going to 5 days again do not worry either. 3 day implantation is fine. Crap quality eggs going in also does not lead to birth defects or other issues.

I have a friend who was told that her egg quality was terrible but they had paid to get this far so they should shove them in. She now has twins.

At some point a decision will be made as to freezing the fertilized eggs. This depends on quality over the first 3 days. If you get frozen (Popsicles) you don't have to go through the stimulation part of IVF next round but do have to do progesterone shots.

Knowing everything I can possibly know about situations is they way ideal with them. This web site, IVF explained is very informative and can assist with understanding the process. I am a numbers person and this site helped me understand the statistics of getting pregnant. For us it was once in 47 years and unfortunately that miracle natural pregnancy ended in miscarriage last year. First try at IVF we were lucky but going into IVF I understood that we had approximately 3:1 odds. It is still impossible not to have your hopes up though for first time luck.

What I will say, and this has no real basis in science, I believe male health is imperative. While alcohol and lifestyle have limited impact on sperm quality, infections can have a big impact on your chances. This impact can be both temporary or permanent. I became very ill due to ecoli poisoning and this infection was discovered everywhere in my body but the most difficult place to kill it was my prostate. By using ICSI they were able to ensure no infection would impact the egg or my wife whereas with normal IVF they could not proceed.

Point being, a couple could be described as infertile one year but this could be due to an infection that once cleared up could make the couple fine the next year. Any changes in sperm quality takes 3 months to come to fruition. So be patient when trying to increase sperm quality.


Any questions about anything let me know. We have experienced. Miscarriage, polyps, female infertility, Male infertility, Ultrasound both male and female, placenta previa (placenta over cervix) Gestational Diabetes.
Edited by h0b0 on Friday 13th June 14:23

Super Slo Mo

5,368 posts

198 months

Friday 13th June 2014
quotequote all
Thanks for the comprehensive info, I shall re read and digest later when not at work.
Slight snag is that we're committed to some big household repairs so that might mean we have to delay the Ivf while our funds recover, although can't do anything until the fibroids are dealt with anyway.
I don't drink these days, and have been taking the 'wellman' supplements. Physically I feel fighting fit, better than I've done in years, due to cutting out alcohol, watching what I eat and getting a reasonable amount of exercise,
If I've understood correctly, I have the fun task of stabbing the wife with a big needle? I will look forward to that smile

h0b0

7,577 posts

196 months

Friday 13th June 2014
quotequote all
There are many different approaches to IVF but all involve stabbing your wife. In our case there were 3 different types of needle varying from pin pick to industrial accident size. Even with the large needles, if you use a stabbing motion then it is not too bad. It's when you try and ease it in that it hurts. My wife had a real problem with injections going in to this and very quickly got over it. We have done the injections in hotels and service station car parks.

I do not know about the costs in the UK because things in the US work slightly different. What I do know is that there is a post code lottery in the UK when it comes to IVF coverage. You will find that you are paying for a service that others are getting for free. So before you commit totally to private check your options.

Here is a picture of ICSI


Super Slo Mo

5,368 posts

198 months

Friday 13th June 2014
quotequote all
We have already checked. We have to pay as she is over the arbitrary 35 year old (think it's actually 34.5) that our health authority has set. People living 5 miles away get it free, as would we if we were a same sex couple. Such is life.
We have lodged an appeal but we are realistic and don't expect any funding assistance.

ruggedscotty

5,624 posts

209 months

Monday 28th July 2014
quotequote all
We had issues - had to provide a sample - not the easiest of things to do and pretty embarassing if you ask me.....

Sample coaxed and into bottle - now that in itself is a feat - you see the size of these little containers ? So you have to get the sample into that container, like FFS man like playing darts at close quarters. aim and fire ? yeap but what about the movements being utilised to coax the sample ? not to be repeated.......

Anyways back for the result - doctor said lazy misshapen and lethargic, said enuf about me what about my sperm....

Its not easy but we erm persevered on ovulation drugs and I had some to increase the testosterone and we did manage before we went down the IVF route.

Hang in there!

Yorkshire Tea

228 posts

200 months

Tuesday 18th November 2014
quotequote all
I have been reading this for a while.

We started on the injections During the summer, our consultant then retired. We took a two week holiday in October and started again the week we got back.

Today she took the test (well 4 to be exact) and all back positive. Absolutely over the moon

Granville

983 posts

171 months

Tuesday 18th November 2014
quotequote all
thumbup brilliant news and congratulations

Legend83

Original Poster:

9,960 posts

222 months

Tuesday 18th November 2014
quotequote all
beer

Super Slo Mo

5,368 posts

198 months

Tuesday 18th November 2014
quotequote all
Congratulations, hope all goes well.

MrGRT

295 posts

163 months

Friday 20th March 2015
quotequote all
A few months have passed since I last commented on this thread, no good news to report.
We've done 2 Fresh cycles and 4 frozen, all in the Oxford F.U. All have resulted in lots of embryos reaching blastocyst stage.
In the last one we even pay for the Pre-implantation genetic screening test.
All test results have been fine according to the Drs.
Only the very first of the cycle was clinically successful but only for 4 weeks then a miscarriage.

Understandably my OH is quite down/depressed, she will be 33 this year and we've been trying for 3 year now. We got two suggestions on our last appointment:
1.- Surrogacy.
2.- Try another cycle, this time putting two embryos. But before that, do another test on my O.H. which If I understood correctly, given an idea of how much her body is rejecting the pregnancy.

Not really sure what to do, of course we don't want a surrogacy if can be avoided but 6 unsuccessful attempts have taken its told on us already.
I do wonder what is the most attempts people have tried and whether they went with two embryos on each attempt.

In our case, we followed recommendations of one embryo, only on the last attempt we tried two.





Dan_1981

17,377 posts

199 months

Friday 20th March 2015
quotequote all
Ovulation sticks - are they reliable?

Even the ones from ebay?

Do you get duds?