Is 3.6 grams of Aspirin actually a lot?
Discussion
Been told elsewhere online that 3.6 grams of Aspirin is a lot of the stuff to be taking every day. On the other hand my reading of the pack instructions seems to suggest it's fine. Supposing you've no problems with your kidneys and no problems with stomach ulcers, is that really likely to be an issue?
I know the usual advice is to take it to your doctor but I don't want paracetamol and I don't want more opiates for various reasons so I can't imagine they can do anything anyway.
I know the usual advice is to take it to your doctor but I don't want paracetamol and I don't want more opiates for various reasons so I can't imagine they can do anything anyway.
Well, considering a normal daily dose is 75mg and if you are having a heart attack you take 300mg, then yes, 3,600mg is a huge amount.
Why are you taking so much?
internet said:
The acutely toxic dose of aspirin is generally considered greater n 150 mg per kg of body mass. Moderate toxicity occurs at doses up to 300 mg/kg, severe toxicity occurs between 300 to 500 mg/kg, and a potentially lethal daose is greater than 500 mg/kg. Chronic toxicity may occur following doses of 100 mg/kg per day for
http://en.m.wikipedia.org/wiki/Aspirin_poisoning#section_2Why are you taking so much?
Thanks all, have a doctor's appointment next week.
Have not answered questions above because, ya'know, it's health
Only point I would make is paracetamol never does anything for me, ibuprofen does but only very weakly. I am confused when it comes to ibuprofen why this should be because my understanding is ibuprofen and aspirin theoretically work on the same pathway... this leads me to suspect that aspirin has an additional mode of action, at least in some people. Just throwing that out there...
Have not answered questions above because, ya'know, it's health
Only point I would make is paracetamol never does anything for me, ibuprofen does but only very weakly. I am confused when it comes to ibuprofen why this should be because my understanding is ibuprofen and aspirin theoretically work on the same pathway... this leads me to suspect that aspirin has an additional mode of action, at least in some people. Just throwing that out there...
Somewhatfoolish said:
I am confused when it comes to ibuprofen why this should be because my understanding is ibuprofen and aspirin theoretically work on the same pathway... this leads me to suspect that aspirin has an additional mode of action, at least in some people. Just throwing that out there...
Stop being such a cox Somewhatfoolish said:
Only point I would make is paracetamol never does anything for me, ibuprofen does but only very weakly. I am confused when it comes to ibuprofen why this should be because my understanding is ibuprofen and aspirin theoretically work on the same pathway... this leads me to suspect that aspirin has an additional mode of action, at least in some people. Just throwing that out there...
They work by a similar mechanism (inhibition of cyclooxygenase), but they're not identical; it's quite possible aspirin works better for you. In particular aspirin is an irreversible inhibitor, whereas ibuprofen is not, so it's possible that your body can reverse the effects of ibuprofen relatively quickly so you experience much reduced effects.Also as with any orally administered drug a large amount of the dosage is metabolised in the liver before it reaches the bloodstream so your liver might just be much better at metabolising ibuprofen and paracetamol than aspirin.
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