How many have been vaccinated so far?
Discussion
Joey Deacon said:
And how long do we think it will be before you are all told you need a booster before lockdown can finally be lifted.Personally I'm expecting annual (at least) boosters based on variants and impact to schools for a long time.
amgmcqueen said:
How are all you double jabbers enjoying your new found freedoms....?
https://apple.news/AqqNUtm_OSUSqzdoi94Q77gItsa coming!
duckson said:
amgmcqueen said:
How are all you double jabbers enjoying your new found freedoms....?
https://apple.news/AqqNUtm_OSUSqzdoi94Q77gItsa coming!
I fully anticipate other countries will follow suit.
vaud said:
How long before people realise that this is a very long haul issue.
Personally I'm expecting annual (at least) boosters based on variants and impact to schools for a long time.
Per Witty this afternoon:Personally I'm expecting annual (at least) boosters based on variants and impact to schools for a long time.
"He said that after five years he thought vaccines would be available that could “hold the line” against a range of variants. He said:
In terms of the medium to longer term, if I look five years out, I would expect us to have polyvalent vaccines which will hold the line to a very large degree against even new variants as they come in, and an ability to respond with vaccination to new variants.
But he said until then new vaccination programmes might be needed. He said:
But the period over the next two or three years, I think new variants may will lead to us having to re-vaccinate or consider at least boosting vaccination as they come through.
We have to just be aware that Covid has not thrown its last surprise at us and there will be there will be several more over the next period."
duckson said:
If the government does not do something soon there will be no airline industry left by next year. Many are already on their knees and were banking on a good summer to see them through the winter. With that looking unlikely, its only a matter of time before they start going under with the economic consequences that brings.KTF said:
If the government does not do something soon there will be no airline industry left by next year. Many are already on their knees and were banking on a good summer to see them through the winter. With that looking unlikely, its only a matter of time before they start going under with the economic consequences that brings.
What else should the government be doing ?EddieSteadyGo said:
This is welcome news!
Seems like the NHS app has been updated to remove the need to cancel your second appointment before being able to check availability.
https://twitter.com/fordie/status/1405281727761711...
So....got a call to hurry up second jabs earlier today as according to the nhs chap it's now 4 week interval.Seems like the NHS app has been updated to remove the need to cancel your second appointment before being able to check availability.
https://twitter.com/fordie/status/1405281727761711...
Which is all rather confusing given the govt and associated advisors spent months since the start of the year saying how smart they were to get better immune response with the longer dosing interval which presumably doesn't matter now......
isaldiri said:
So....got a call to hurry up second jabs earlier today as according to the nhs chap it's now 4 week interval.
Which is all rather confusing given the govt and associated advisors spent months since the start of the year saying how smart they were to get better immune response with the longer dosing interval which presumably doesn't matter now......
Yes but that was to extend the number of people that could get the first jab, an approach that worked when we were more supply constrained and against the earlier variants.Which is all rather confusing given the govt and associated advisors spent months since the start of the year saying how smart they were to get better immune response with the longer dosing interval which presumably doesn't matter now......
It's a moving target, and they are adapting the strategy... which is fair in my book. I don't see it as confusing - it should not be a rigid playbook.
isaldiri said:
EddieSteadyGo said:
This is welcome news!
Seems like the NHS app has been updated to remove the need to cancel your second appointment before being able to check availability.
https://twitter.com/fordie/status/1405281727761711...
So....got a call to hurry up second jabs earlier today as according to the nhs chap it's now 4 week interval.Seems like the NHS app has been updated to remove the need to cancel your second appointment before being able to check availability.
https://twitter.com/fordie/status/1405281727761711...
Which is all rather confusing given the govt and associated advisors spent months since the start of the year saying how smart they were to get better immune response with the longer dosing interval which presumably doesn't matter now......
It seems sensible to change tack slightly under the new circumstance and accept maybe a slightly reduced overall immune response.
Surely continual reassessment should be an important aspect of management.
isaldiri said:
So....got a call to hurry up second jabs earlier today as according to the nhs chap it's now 4 week interval.
Which is all rather confusing given the govt and associated advisors spent months since the start of the year saying how smart they were to get better immune response with the longer dosing interval which presumably doesn't matter now......
In fairness was the 12 week dose interval leading to higher efficacy not primarily aimed at the AZ vaccine, which from what I can tell is a "slow burner" and can take some time to do it's stuff? 4 weeks sounds more in line with the recommendations for the mRNA vaccines. Which is all rather confusing given the govt and associated advisors spent months since the start of the year saying how smart they were to get better immune response with the longer dosing interval which presumably doesn't matter now......
As you know I'm on "Team Monkey Snot", my 2nd jab is still booked in for 12 weeks after the first in August, and haven't been asked to change just yet. I do need to call them up, as my 2nd jab is 20 miles away and not sure if I fancy driving that far after how spaced I felt after jab 1.
Nickgnome said:
I thought that the 12week period was to ensure more vulnerable people got their first dose as a priority and the slightly increased immune response after 12weeks was a beneficial side effect.
It seems sensible to change tack slightly under the new circumstance and accept maybe a slightly reduced overall immune response.
Surely continual reassessment should be an important aspect of management.
Indeed. Only a fool sticks to a strategy when the environment changes and level of information increases.It seems sensible to change tack slightly under the new circumstance and accept maybe a slightly reduced overall immune response.
Surely continual reassessment should be an important aspect of management.
bodhi said:
In fairness was the 12 week dose interval leading to higher efficacy not primarily aimed at the AZ vaccine, which from what I can tell is a "slow burner" and can take some time to do it's stuff? 4 weeks sounds more in line with the recommendations for the mRNA vaccines.
As you know I'm on "Team Monkey Snot", my 2nd jab is still booked in for 12 weeks after the first in August, and haven't been asked to change just yet. I do need to call them up, as my 2nd jab is 20 miles away and not sure if I fancy driving that far after how spaced I felt after jab 1.
Which is the point I made at the end of Jan when it was clear infections were falling very sharply and there was no longer any reason to continue the desperation move chosen at the end of Dec to increase dose intervals so significantly. As you know I'm on "Team Monkey Snot", my 2nd jab is still booked in for 12 weeks after the first in August, and haven't been asked to change just yet. I do need to call them up, as my 2nd jab is 20 miles away and not sure if I fancy driving that far after how spaced I felt after jab 1.
One of my posts then was there was no longer any reason to delay the mRNA ones as much. The AZN trial was such a bloody mess it probably didn't entirely matter which interval was used as at one point they ended up showing single doses had higher efficacy than 2.
If anything had shorter intervals been used though, it would by now be much clearer if ViTT is actually an issue on second doses The numbers don't exactly look promising and oddly enough I see the mhra now has changed their yellow card reporting to not split up first and second dose cases any longer......
isaldiri said:
Which is the point I made at the end of Jan when it was clear infections were falling very sharply and there was no longer any reason to continue the desperation move chosen at the end of Dec to increase dose intervals so significantly.
One of my posts then was there was no longer any reason to delay the mRNA ones as much. The AZN trial was such a bloody mess it probably didn't entirely matter which interval was used as at one point they ended up showing single doses had higher efficacy than 2.
If anything had shorter intervals been used though, it would by now be much clearer if ViTT is actually an issue on second doses The numbers don't exactly look promising and oddly enough I see the mhra now has changed their yellow card reporting to not split up first and second dose cases any longer......
Don't disagree that the initial trial and dosing strategy was a bit of a shambles, however from studies done since it does seem as if they "dropped on" to the best strategy for AZ - more by luck than judgement of course. However the evidence for longer gaps between doses for the mRNA vaccines isn't great as you say. One of my posts then was there was no longer any reason to delay the mRNA ones as much. The AZN trial was such a bloody mess it probably didn't entirely matter which interval was used as at one point they ended up showing single doses had higher efficacy than 2.
If anything had shorter intervals been used though, it would by now be much clearer if ViTT is actually an issue on second doses The numbers don't exactly look promising and oddly enough I see the mhra now has changed their yellow card reporting to not split up first and second dose cases any longer......
Of course if we were being really sensible and data-led, anyone with a positive PCR or Antibody test would only be getting one dose full stop as that seems to give even better immunity than a double dose, rendering the second dose fairly redundant. However considering PHE have taken until today to publish any real data on immunity from infection, that would probably be a bit much to ask really.
vaud said:
isaldiri said:
The AZN trial was such a bloody mess it probably didn't entirely matter which interval was used as at one point they ended up showing single doses had higher efficacy than 2.
Source? (I'm genuinely interested)bodhi said:
Of course if we were being really sensible and data-led, anyone with a positive PCR or Antibody test would only be getting one dose full stop as that seems to give even better immunity than a double dose, rendering the second dose fairly redundant. However considering PHE have taken until today to publish any real data on immunity from infection, that would probably be a bit much to ask really.
Sensible and data led? 
on which planet have you been on this last 15 months?In any case, it's more I find it rather entertaining how 'the science' constantly manages to magically change to reflect whatever the government is trying to push. When they needed to push out intervals the data was found to fit. Now all that data which justified the move suddenly doesn't matter. Because variant of course.......
Edit on a reread, I've incorrectly stated earlier 2nd dose vitt isn't being recorded on the yellow card data. It's buried somewhere in the writeup but a bit less obvious to find, my bad. It's just the split of incidence is missing from the age table now. +4 from last week for second doses. +18 in total.
Edited by isaldiri on Thursday 17th June 17:22
Vasco said:
What else should the government be doing ?
Accepting that this is now an endemic virus, that the vulnerable are vaccinated, that so far no variants have evaded the vaccine and let everyone get on with their lives to generate wealth to pay taxes to pay for this s
t storm we have been through for the last 15 months. Steve vRS said:
Vasco said:
What else should the government be doing ?
Accepting that this is now an endemic virus, that the vulnerable are vaccinated, that so far no variants have evaded the vaccine and let everyone get on with their lives to generate wealth to pay taxes to pay for this st storm we have been through for the last 15 months. amgmcqueen said:
How are all you double jabbers enjoying your new found freedoms....?
Quite a lot, thanks. Since I’ve had mine I’m now happy to visit my parents and my brothers, I’m going back doing some track days, and have taken my home up North out of mothballs as I am comfortable travelling there again, whether by air or on the ferry.I’ve now booked our family holiday in Cyprus, and hope to get to see the in-laws in Bordeaux and Antibes next month.
After over a year of needing to avoid this sort of thing it’s a real relief.
How about you, still eating pot noodles, watching repeats of The Bill and having a w
k while your mam’s out at the shops?Gassing Station | News, Politics & Economics | Top of Page | What's New | My Stuff