Wegovy Anti-chubster injection-pen things

Wegovy Anti-chubster injection-pen things

Author
Discussion

LeftmostAardvark

1,486 posts

172 months

Monday 11th November
quotequote all
Dbag101 said:
https://www.forbes.com/sites/katherinehignett/2024...

Apparently one of the side effects of one of these type of drugs is death. Over to you then.
Ibuprofen - 2000 deaths

Paracetamol- 261 deaths

Amitriptyline - 270 deaths

Contraceptive pill - 380 deaths

Tampons - 3 deaths a year due to toxic shock

Covid vaccine - 59 deaths

Your point is?

Edited by LeftmostAardvark on Monday 11th November 18:35

Hugo Stiglitz v2

344 posts

2 months

Monday 11th November
quotequote all
said:
That the drugs you list are used by many many many many people globally daily so of course the deaths will be higher...

bloomen

7,484 posts

167 months

Monday 11th November
quotequote all
There'll be someone somewhere who'll always respond in the worst possible way while millions chug along just fine.

I'd be more concerned with the effects of long term use, which seems to be the recommendation if you want to stay on a level.

I'm sure I'd happily pop a bunch more drugs if they'd been around for 500 years or more.


Throttlebody

2,469 posts

62 months

Monday 11th November
quotequote all
Nomad 5 said:
Throttlebody said:
Very interesting. Any negative side effects?

Personally I don’t need it, but friends have been considering it recently.
No, none of note.

Very pleased so far.

You can let your 'friend' know. wink

Edited by Nomad 5 on Monday 11th November 16:49
They’re putting lots of deep thought into it. Don’t want to expose themselves to unnecessary exposure smile

LeftmostAardvark

1,486 posts

172 months

Monday 11th November
quotequote all
Throttlebody said:
They’re putting lots of deep thought into it. Don’t want to expose themselves to unnecessary exposure smile
Very minor nausea for a few hours the following day after I moved up from 2.5 to 5, otherwise nothing except positive effects.

Nomad 5

155 posts

80 months

Tuesday 12th November
quotequote all
Throttlebody said:
They’re putting lots of deep thought into it. Don’t want to expose themselves to unnecessary exposure smile
I consider it a lifestyle change.

Previous occasional nausea has reduced dramatically to the point of being non existent. Only the odd blip.

I can change pharmacies when i want to too, which is worth bearing in mind. In fact i might fairly soon. smile

I have no affilliation to this particular pharmacy so happy to move again.

Edited by Nomad 5 on Tuesday 12th November 15:40

LeftmostAardvark

1,486 posts

172 months

Tuesday 12th November
quotequote all
Nomad 5 said:
I consider it a lifestyle change.

Previous occasional nausea has reduced dramatically to the point of being non existent. Only the odd blip.

I can change brands when i want to too, which is worth bearing in mind. In fact i might fairly soon. smile
Do you mean brands (Mounjaro to Wegovy) or pharmacies?

Edit: I always understood there needed to be a few weeks between switching from one drug to another - think it’s recommended as five weeks

Nomad 5

155 posts

80 months

Tuesday 12th November
quotequote all
LeftmostAardvark said:
Nomad 5 said:
I consider it a lifestyle change.

Previous occasional nausea has reduced dramatically to the point of being non existent. Only the odd blip.

I can change brands when i want to too, which is worth bearing in mind. In fact i might fairly soon. smile
Do you mean brands (Mounjaro to Wegovy) or pharmacies?

Edit: I always understood there needed to be a few weeks between switching from one drug to another - think it’s recommended as five weeks
Yes, you're right, pharmacies. Updated my post.


LeftmostAardvark

1,486 posts

172 months

Tuesday 12th November
quotequote all
As I close in on my second jab at 5mg, after about a month where I lost just shy of 2st (3.5 to go though frown ), these are my thoughts:
1. I didn’t have any side effects (maybe a couple of hours of nausea for a couple of hours after I went up to 5mg the first time, but so little as to barely noticeable), but I did get pretty much instant food suppression. It is really hard to explain, but the ‘drive’ goes away and (for me) anything remotely processed became repellant. From your world revolving around food (wanting it, resisting it, regretting it etc), it holds no interest. You almost have to remind yourself / force yourself to eat, which leads me to:
2. Protein, protein, protein. I find the natural protein-rich nut bars like Kind or Be Naturas are good. Also, I find myself planning meals solely around high protein.
3. Hydrate. I don’t particularly like the taste of water and most cordial / squash feels artificial so I found waterdrop, which has really helped me not struggle with drinking regularly. I think they’ve got a pop up shop in St Pancras, but I got it online.
4. You will get the entire range of emotions if / when you tell people, from curiosity, through to ambivalence, (sadly) some well meaning but deeply unhelpful ‘advice’, and in some cases outright disgust.
5. The cost is high but the food bill drops considerably so it evens out. Don’t forget the existing members of your family, particularly if you are the primary cook / chef / food shopper.
6. The suppression wears off after about 5 days (at the start anyway, for me it was less so after a few weeks), it’s frustrating and scary - great progress is so easy to undo in an ill-judged moment, but the upside is I find the lack of suppression can be looked upon as a way to train new habits and understand the food drive a bit better. If you understand it (and how it feels when it isn’t there), you can step outside it and reduce its hold on you.
7. The needles are so small, you don’t feel them.
8. There’s a lot of info about getting the ‘5th dose’ online. It’s expensive, so I tried (and succeeded) with the first dose.
9. Strength training is probably a good option to minimise muscle loss, my circumstances meant that has been fairly informal (currently renovating half an acre of recently bought garden and dealing with a stressful job and long commute), but I do have more motivation to do strenuous activity.
10. My blood pressure has dropped much closer to normal range, and regular waking to migraine has reduced (only one since I started taking this vs 3-4 a week). Not sure if that’s the drug or the weight loss, probably a combo.

Still to find out for me:
1. What happens as I go up the doses, in terms of suppression and side effects, and whether the weight loss stays linear as it is at the moment, or tail off.
2. How to manage maintenance when I get to the right weight. I’m thinking reduce back down to minimal possible dose and then space the doses out to 10, 14, 21 days.

lrdisco

1,552 posts

95 months

Thursday 14th November
quotequote all
Lost 34kg since start of May. Had a weight loss pause but now doing well again. On 15mg Mounjaro.
Gym 5 x a week now.
Only recent downside recently is my alcohol cravings have returned.
Never had any side effects at all.

StoutBench

405 posts

36 months

Thursday 14th November
quotequote all
lrdisco said:
Lost 34kg since start of May. Had a weight loss pause but now doing well again. On 15mg Mounjaro.
Gym 5 x a week now.
Only recent downside recently is my alcohol cravings have returned.
Never had any side effects at all.
That's incredible, well done!

GiantEnemyCrab

7,728 posts

211 months

Thursday 14th November
quotequote all
Definitely recommend reading / trying Allen Carr method for weight loss before going for medicine option. Costs less than 10 quid and could rewire your brain in the same way it does for fags and booze.

StoutBench

405 posts

36 months

Thursday 14th November
quotequote all
GiantEnemyCrab said:
Definitely recommend reading / trying Allen Carr method for weight loss before going for medicine option. Costs less than 10 quid and could rewire your brain in the same way it does for fags and booze.
Not what this thread is about. Thanks

LeftmostAardvark

1,486 posts

172 months

Thursday 14th November
quotequote all
lrdisco said:
Lost 34kg since start of May. Had a weight loss pause but now doing well again. On 15mg Mounjaro.
Gym 5 x a week now.
Only recent downside recently is my alcohol cravings have returned.
Never had any side effects at all.
Amazing result, congratulations. If you’ve reached your goal, what are your thoughts about how to maintain? Are you going to go back down the doses or spread them out?

Dunclane

1,267 posts

177 months

Friday 15th November
quotequote all
I have had my first pen of Mounjaro delivered today.

I am 44, 5'7 and 102kg.

I go to the gym 2-3 times per week do over an hour of cardio each time plus some weights and whilst I feel fit and healthy I CANNOT shift this bloaty mid section.

I've finally realised I'm never going to out train my diet which while it's not a bad diet it's just portion control.

Whilst I don't constantly eat throughout the day I have always been a fast eater even when I was a kid, it is impossible for me to leave food on a plate, just can't do it! I can't even leave leftovers in the kitchen.

For me I think it's two things. firstly food noise which is a term I hadn't heard until Mounjaro became a thing, when I feel hungry it's all consuming and all I can think about.

Then when I do eat, I eat so quickly I don't let my stomach catch up with my brain. I've tried and tried to eat slower, putting fork down between mouthfuls but just can't do it.

I'm hoping using this method gives me some cognitive reset.

Dunclane

1,267 posts

177 months

Friday 15th November
quotequote all
LeftmostAardvark said:
As I close in on my second jab at 5mg, after about a month where I lost just shy of 2st (3.5 to go though frown ), these are my thoughts:
1. I didn’t have any side effects (maybe a couple of hours of nausea for a couple of hours after I went up to 5mg the first time, but so little as to barely noticeable), but I did get pretty much instant food suppression. It is really hard to explain, but the ‘drive’ goes away and (for me) anything remotely processed became repellant. From your world revolving around food (wanting it, resisting it, regretting it etc), it holds no interest. You almost have to remind yourself / force yourself to eat, which leads me to:
2. Protein, protein, protein. I find the natural protein-rich nut bars like Kind or Be Naturas are good. Also, I find myself planning meals solely around high protein.
3. Hydrate. I don’t particularly like the taste of water and most cordial / squash feels artificial so I found waterdrop, which has really helped me not struggle with drinking regularly. I think they’ve got a pop up shop in St Pancras, but I got it online.
4. You will get the entire range of emotions if / when you tell people, from curiosity, through to ambivalence, (sadly) some well meaning but deeply unhelpful ‘advice’, and in some cases outright disgust.
5. The cost is high but the food bill drops considerably so it evens out. Don’t forget the existing members of your family, particularly if you are the primary cook / chef / food shopper.
6. The suppression wears off after about 5 days (at the start anyway, for me it was less so after a few weeks), it’s frustrating and scary - great progress is so easy to undo in an ill-judged moment, but the upside is I find the lack of suppression can be looked upon as a way to train new habits and understand the food drive a bit better. If you understand it (and how it feels when it isn’t there), you can step outside it and reduce its hold on you.
7. The needles are so small, you don’t feel them.
8. There’s a lot of info about getting the ‘5th dose’ online. It’s expensive, so I tried (and succeeded) with the first dose.
9. Strength training is probably a good option to minimise muscle loss, my circumstances meant that has been fairly informal (currently renovating half an acre of recently bought garden and dealing with a stressful job and long commute), but I do have more motivation to do strenuous activity.
10. My blood pressure has dropped much closer to normal range, and regular waking to migraine has reduced (only one since I started taking this vs 3-4 a week). Not sure if that’s the drug or the weight loss, probably a combo.

Still to find out for me:
1. What happens as I go up the doses, in terms of suppression and side effects, and whether the weight loss stays linear as it is at the moment, or tail off.
2. How to manage maintenance when I get to the right weight. I’m thinking reduce back down to minimal possible dose and then space the doses out to 10, 14, 21 days.
Really useful stuff, thank you for sharing thumbup

evolution380

59 posts

48 months

Friday 15th November
quotequote all
I'm not entirely sure why people feel the need to get moral high ground and ridicule other peoples decisions to take a medication or scaremonger with the side effects.

This is a personal decision for anyone that looks to take this medication. People should research any medication, weigh up the risks and consult with their doctor. For some morbidly obese people, taking mounjaro is going to drastically reduce many health issues and risks associated with their obesity. Not to mention reduce the amount of cardiolgy issues, hip/knee replacements and diabetes etc. further down the line. I genuinely see these injections as a net positive to the NHS in the long term.

Side effects are a risk with any medication, whilst the side effects vary. S&D is the most likely side effect that people will find with serious side effects being much less likely. That's where the titration also comes in, starting at a low dose most of the time will show peoples tolerance to this medication and hopefully present mild side effects at a lower dose rather than diving straight into the deep end.

Obesity is a massive burden to the NHS, people paying out of their own pocket for medication which will make them less of a statistic is no skin off my nose and can't understand why it is for others. Who cares if it's an 'easier' road?

The 'will power' thing isn't linear, what may be enough will power for one person to stay in shape or lose weight won't be enough for another person to not be obese if their cravings and ravenous hunger signalling are much louder than the average persons.

I mean some really thin people aren't that way because they have will power, they are that way as they are just dis-interested in food and don't feel ravenous or deal with cravings in their day to day life. Mounjaro replicates this scenario for people who have never felt that way, and gives them the oppurtunity to make lifestyle changes which will hopefully see them keep the weight off long term.

Losing weight can definitely be a test of will power, more or less for different people. I'm testament to that myself and I can take pride in that, but nobody should be made to feel guilty for taking modern medicine if they are seeking to better themselves and lessen the burden on the NHS.

A lot of people that will take mounjaro have probably been on constant diets, lost and gained weight and just feel demoralised with going around in circles. I'm glad GLP1-S have given these people a chance to make the change permantly.


lrdisco

1,552 posts

95 months

Saturday 16th November
quotequote all
LeftmostAardvark said:
Amazing result, congratulations. If you’ve reached your goal, what are your thoughts about how to maintain? Are you going to go back down the doses or spread them out?
My goal is another 24kg away. Then plan to stay on it forever but at a lower dose. There are ways to do this.

Dbag101

242 posts

2 months

Saturday 16th November
quotequote all
Apparently, a big chunk of the issues, is down to gut health. So, don’t extract the urine with your lifestyle, eat sensibly, exercise regularly, and keep an eye on your gut health ( it seems to be more important than previously realised ) and you ( may ) not need to rely on a ( largely ) unproven drug, to achieve your unsustainable ( possibly in my opinion ) results smile

StoutBench

405 posts

36 months

Saturday 16th November
quotequote all
Dbag101 said:
Apparently, a big chunk of the issues, is down to gut health. So, don’t extract the urine with your lifestyle, eat sensibly, exercise regularly, and keep an eye on your gut health ( it seems to be more important than previously realised ) and you ( may ) not need to rely on a ( largely ) unproven drug, to achieve your unsustainable ( possibly in my opinion ) results smile
What are you looking to achieve here? Genuinely interested in this.