What's the best anti spam software then?

[philthy]

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After having my own domain name, and personal email address kept private for a couple of years, I'm now getting spam. Strangely, it coincides with my missus starting to get the same stuff. She hardly ever uses email, and keeps her address very private, same as me. The only thing we can put it down to, is somebody close to us, that has us both in their address book, has a virus.
Anyhoo, can anybody recommend good spam filtering software. I'm prepared to spend long hours training it, if need be.
Thanks in advance
Phil