Anyone know about 'reprogramming' DNA treatment?
Anyone know about 'reprogramming' DNA treatment?
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skeggysteve

Original Poster:

5,724 posts

246 months

Monday 13th January 2020
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Can't type anymore than the thread title, but hope someone can give me some insight.

anonymous-user

83 months

Monday 13th January 2020
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reprogramming dna? Do you stem cells as reprogramming dna doesn't really happen yet.

skeggysteve

Original Poster:

5,724 posts

246 months

Monday 13th January 2020
quotequote all
Thesprucegoose said:
reprogramming dna? Do you stem cells as reprogramming dna doesn't really happen yet.
Currently googling like mad but it's some Australian doctor and it could be a cure.

Just clutching at straws.

anonymous-user

83 months

Monday 13th January 2020
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cure for what? I guess cancer. There will never be a cure as the way the cells work you don't cure them, it is a range of factors that cause 'cancer' we end up with.

There is a treatment which uses the body immune system to fight the cancer, immunotherapy. I think the USA is the only place you can have treatment, it is in the many tens of thousands, and no guarantee.

skeggysteve

Original Poster:

5,724 posts

246 months

Monday 13th January 2020
quotequote all
Website link to the australian doctors

https://www.imugene.com/

As I said just clutching at straws.

anonymous-user

83 months

Monday 13th January 2020
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you can modify viruses yo use them as a way to inject dna into a host, they think viruses have had a part in our evolution. This is nothing new our DNA has remnants of Virus DNA. It would be a potential carry for immunotherapy. which it seems this company is. This is all very green. The problem is the complexity that it may work for one person but not another.

The best bet is immunotherapy that is being used currently, but it has it advantages and disadvantages. At the momment there is no real cure.

BevR

825 posts

172 months

Tuesday 14th January 2020
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skeggysteve said:
Website link to the australian doctors

https://www.imugene.com/

As I said just clutching at straws.
Which of the technologies are you looking for information about? These are not snake oil salesmen, the technology (especially for immunotherapy is a big field. Here is a video that shows how it works:

https://www.youtube.com/watch?v=jDdL2bMQXfE


Oncolytic viruses are an older idea but haven't gained the same kind of traction yet (not to say they do not or wont work, they have just proved tricky to engineer) and are explained here:

https://www.youtube.com/watch?v=zwlCkVnUgWQ


Is there a particular product/technology/target you want more information on?


BevR

825 posts

172 months

Tuesday 14th January 2020
quotequote all
Thesprucegoose said:
cure for what? I guess cancer. There will never be a cure as the way the cells work you don't cure them, it is a range of factors that cause 'cancer' we end up with.

There is a treatment which uses the body immune system to fight the cancer, immunotherapy. I think the USA is the only place you can have treatment, it is in the many tens of thousands, and no guarantee.
I think you are talking about CAR-T cells. CAR-T immunotherapy is performed in the UK but only for a very small number of diseases, many of which are still at clinical trial stage. It can work wonders for some (e.g CD19 B cell leukemia) but it is very cancer and target specific. The cost is in the hundred of thousands but it is a last line of defense treatment, the first approved one is Kymriah : https://en.wikipedia.org/wiki/Tisagenlecleucel

As a general term there are a lot of immunotherapies that are approved for clinical use: https://en.wikipedia.org/wiki/Cancer_immunotherapy

skeggysteve

Original Poster:

5,724 posts

246 months

Tuesday 14th January 2020
quotequote all
Thank you for all the replies and links, I will pass them on.

Yes it is cancer, our 32 year old son was diagnosed with bowel cancer 2 years ago and it has got worse.

As I said clutching at straws.

Baby Shark doo doo doo doo

15,078 posts

198 months

Tuesday 14th January 2020
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skeggysteve said:
Thank you for all the replies and links, I will pass them on.

Yes it is cancer, our 32 year old son was diagnosed with bowel cancer 2 years ago and it has got worse.

As I said clutching at straws.
So sorry to read this frown

Best of luck to your son in overcoming it

Gromm

890 posts

86 months

Tuesday 14th January 2020
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@ the OP

Steve, I’m sorry to hear this, naturally every case is different, but the last thing you want to do is to let go of those straws. Apologies, if you’ve seen it already, this is a very encouraging story and outcome of conventional treatment LINK Keep on fighting and all the best!