High Cortisol and Post Op Blues

[Glassman]

Does anyone have any experience of high cortisol?

Based on contributors and some of the symptoms, I've all but convinced myself that I may have high cortisol. Weight gain (particularly in belly) increased fatigue, high blood pressure, borderline pre diabetic (according to health check). I've also recently experienced emotional instability, anxiety, and sleeplessness but I'm putting much of this down to post operation blues (back in July went in for surgery: six hour stint to remove a bowel tumour plus insert bi-lateral stents for a kidney stone procedure a few weeks later).

Before the operation I've always had the ability to lose weight easily (and put it back on quickly). The cortisol explanation just seems to be very relevant, especially considering my age.

[Yahonza]

You can tested perhaps if you ask your GP - for hypercortisolism.
Unlikely it's that though, more likely the rebound shock after extensive surgery and anaesthesia - and anaesthesia in particular.
It's a pity there isn't any real follow up for people post-surgery.
Probably not very helpful but have a chat with your GP.

[foccer]

Sounds very much like the symptoms i have for Hyperparathyroidism - also known as Conn's Syndrome except its excess Aldosterone rather than Cortisone.

Shed loads of tests to work it out though.

Both high cortisol and high aldosterone are (I think) caused by the same thing which is tumors on the adrenal glands which i would suspect your scans/surgery would have spotted already

Edited by foccer on Monday 23 March 18:54

[gangzoom]

foccer said:

Sounds very much like the symptoms i have for Hyperparathyroidism - also known as Conn's Syndrome except its excess Aldosterone rather than Cortisone.

Shed loads of tests to work it out though.

Both high cortisol and high aldosterone are (I think) caused by the same thing which is tumors on the adrenal glands which i would suspect your scans/surgery would have spotted already

I think this is a good example why car forums are NOT a good place for medical advice or opinion.

[RSTurboPaul]

gangzoom said:

foccer said:

Sounds very much like the symptoms i have for Hyperparathyroidism - also known as Conn's Syndrome except its excess Aldosterone rather than Cortisone.

Shed loads of tests to work it out though.

Both high cortisol and high aldosterone are (I think) caused by the same thing which is tumors on the adrenal glands which i would suspect your scans/surgery would have spotted already

I think this is a good example why car forums are NOT a good place for medical advice or opinion.

Because... ?

[gangzoom]

RSTurboPaul said:

Because... ?

This is the Renin, Aldosterone pathway - Conn's syndrome.



This is the pituitary gland axis for Cortisol.




This is the parathyroid gland axis - PTH/bone.



A car forum is not the place to try and explain/work out the pathophysiology of the neuro endocrine system, your local qualified health care institution is a much better place to discuss these matters .

Cushing disease is something that can be caused by isolated ACTH or ACTH like molecules secretion, true Cushing's disease is rare but can be picked up through the right blood chemistry without imaging. But again seek professional medical advice!!!

Edited by gangzoom on Monday 23 March 19:48

[RSTurboPaul]

gangzoom said:

I think this is a good example why car forums are NOT a good place for medical advice or opinion.

gangzoom said:

This is the Renin, Aldosterone pathway - Conn's syndrome.

https://media.springernature.com/lw685/springer-st...


This is the pituitary gland axis - Cortisol

rhttps://zerotofinals.com/wp-content/uploads/Adren...


This is the parathyroid gland axis - PTH/bone

https://d1j63owfs0b5j3.cloudfront.net/term/images/...


A car forum is not the place to try and explain/work out the pathophysiology of the neuro endocrine system :smile:

Without wishing to cause any offence, one might interpret this response as 'you peasants are too simple to understand such a subject and I am therefore not even going to attempt a simplified explanation of the differences and/or similarities between the two mechanisms or clear up any confusion'.


edit:

I note your additional text added while I was being tardy in finishing a quoted reply (thanks, forum software, for only given me a completely blank post when I pressed 'quote', necessitating copy and pasting everything).

While it appears useful, thank you, it does not appear to directly respond to any points made in earlier posts; rather, it raises what appears to be an additional discussion point without an explanation suitable for a layman.

The depth of knowledge seems high on the subject so I think all parties would appreciate any 'simplified' version it may be possible to provide.

Edited by RSTurboPaul on Monday 23 March 20:33

[Yahonza]

gangzoom said:

RSTurboPaul said:

Because... ?

This is the Renin, Aldosterone pathway - Conn's syndrome.



This is the pituitary gland axis for Cortisol.

[Img]https://zerotofinals.com/wp-content/uploads/Adrenal-Axis-3-300x249.jpg[/thumb]


This is the parathyroid gland axis - PTH/bone.

[Img]https://d1j63owfs0b5j3.cloudfront.net/term/images/calcium-homeostasis-parathyroid-hormone-3399.png[/thumb]

A car forum is not the place to try and explain/work out the pathophysiology of the neuro endocrine system, your local qualified health care institution is a much better place to discuss these matters .

Edited by gangzoom on Monday 23 March 19:48

That's why it was suggested a few posts up for the OP to talk to their GP - rather than obfuscate matters with complex endocrinology diagrams that don't answer the question.

[shirt]

gangzoom said:

foccer said:

Sounds very much like the symptoms i have for Hyperparathyroidism - also known as Conn's Syndrome except its excess Aldosterone rather than Cortisone.

Shed loads of tests to work it out though.

Both high cortisol and high aldosterone are (I think) caused by the same thing which is tumors on the adrenal glands which i would suspect your scans/surgery would have spotted already

I think this is a good example why car forums are NOT a good place for medical advice or opinion.

He’s right though.

I had a chest scan after a car accident (car related content, tick) which revealed I had no trauma but did have a massive gallstone and a small tumour on my adrenal gland.

I get tests every 6 mths and an MRI every year. Cortisol has been high last 2 checks but the scan reveals the tumour hasn’t grown and shouldn’t be causing the issues it is due to size and location. Working with my endo on lifestyle factors before she elects for surgery.

[foccer]

shirt said:

Working with my endo on lifestyle factors before she elects for surgery.

there is a blood test they can do where they check the output of each adrenal gland to see if the high levels are attributed to one gland or both. Worth getting that done before opting for gland removal as you may be removing it for no reason