Depends upon your application. Note though - some boxes specify GL4 not GL5, as GL5 is slightly too acidic for the bearings (eg BGH recommend GL4 synthetics).
The choice between GL4 and GL5 also depends on the synchromesh -for many older boxes (eg Muncie, T10) GL5 is too "slippery" for the synchro to work correctly, giving baulky shifts.