I know this sounds like I'm going insane, but when I scroll up or down a page in I.E. using the scroll bar on my touchpad (Dell laptop), the music I'm playing using iTunes skips, and keeps doing so till the page stops moving...
I think it must be a bug in the new itunes because my computer is nowhere near its maximum capacity when I'm doing this, it seems to happen with mine only on scrolliing adverts.