Normal paracetamol dosage?
Discussion
Folks,
I was under the impression that it was 400mg (2x200mg caps) up to 4 Times a day.
However, having just visited my local pharmacy in Ecuador I bought a blister pack of Paracetamol 1g.
Presumably each capsule is 1g? These are Argentine and I remember from living there that other analgesics tend to have similarly huge pills such as 800mg ibuprofen etc.
Is it just a measuring system difference or are these really 5 times stronger than UK stuff? I'll only take one at a time if that's the case!
I was under the impression that it was 400mg (2x200mg caps) up to 4 Times a day.
However, having just visited my local pharmacy in Ecuador I bought a blister pack of Paracetamol 1g.
Presumably each capsule is 1g? These are Argentine and I remember from living there that other analgesics tend to have similarly huge pills such as 800mg ibuprofen etc.
Is it just a measuring system difference or are these really 5 times stronger than UK stuff? I'll only take one at a time if that's the case!
Flat6er said:
Yup. 1000mg or one gram up to 4 times a day. So pop one of them each 4 hours and you'll be fine.
not for long you won't, don't do that much for more than 3 or 4 daysEdited by Flat6er on Wednesday 19th October 23:19
very easy to do permanent liver damage with paracetamol, very dangerous drug
maximum recommended dose for healthy adults is 3g a day
6g a day over 48hrs can be all you need for toxicity
ask at your local liver transplant specialist for more details

scotlandtim said:
Hugo a Gogo said:
not for long you won't, don't do that much for more than 3 or 4 days
maximum recommended dose for healthy adults is 3g a day
Can you provide a citation for the above?maximum recommended dose for healthy adults is 3g a day
That said, I would personally never take the stuff at all never mind approach 4g/day.
BNF:
Mild to moderate pain
Pyrexia
By mouth
Adult
0.5–1 g every 4–6 hours; maximum 4 g per day.
By intravenous infusion
Adult (body-weight up to 50 kg)
15 mg/kg every 4–6 hours, dose to be administered over 15 minutes; maximum 60 mg/kg per day.
Adult (body-weight 50 kg and above)
1 g every 4–6 hours, dose to be administered over 15 minutes; maximum 4 g per day.
By rectum
Adult
0.5–1 g every 4–6 hours; maximum 4 g per day.
Mild to moderate pain
Pyrexia
By mouth
Adult
0.5–1 g every 4–6 hours; maximum 4 g per day.
By intravenous infusion
Adult (body-weight up to 50 kg)
15 mg/kg every 4–6 hours, dose to be administered over 15 minutes; maximum 60 mg/kg per day.
Adult (body-weight 50 kg and above)
1 g every 4–6 hours, dose to be administered over 15 minutes; maximum 4 g per day.
By rectum
Adult
0.5–1 g every 4–6 hours; maximum 4 g per day.
some pharma firms have revised their guidelines down to 3g a day
http://www.propharmaconsultants.com/CCG_PDF/38_CCG...
many sources are still saying max 4 g in a day
I'm not a Doctor, but I'm lead to believe that even a week of 4g a day can cause you serious harm
stuff like drinking alcohol, not eating (because you're in pain), can increase your risks
http://www.propharmaconsultants.com/CCG_PDF/38_CCG...
many sources are still saying max 4 g in a day
I'm not a Doctor, but I'm lead to believe that even a week of 4g a day can cause you serious harm
stuff like drinking alcohol, not eating (because you're in pain), can increase your risks
Hugo a Gogo said:
some pharma firms have revised their guidelines down to 3g a day
http://www.propharmaconsultants.com/CCG_PDF/38_CCG...
many sources are still saying max 4 g in a day
I'm not a Doctor, but I'm lead to believe that even a week of 4g a day can cause you serious harm
stuff like drinking alcohol, not eating (because you're in pain), can increase your risks
That's a 2 yr old Amercian paper - fairly non conclusive IMO - Paracetamol is known as ahighly toxic substance, many say if it was invented today it would never be passed as safe, however current UK guidelines still sit at 4g per day, and there are many people, who use it to the maximum dose who haven't developed any toxicity at this point - however, like anything, use with caution!http://www.propharmaconsultants.com/CCG_PDF/38_CCG...
many sources are still saying max 4 g in a day
I'm not a Doctor, but I'm lead to believe that even a week of 4g a day can cause you serious harm
stuff like drinking alcohol, not eating (because you're in pain), can increase your risks
that's 2 years old, how old is the 4g guideline?
many people are using it without toxicity, sure, that doesn't mean it's not a risk - and not many are using the maximum dose day-in day-out with harm, if any at all
If a manufacturer says 'don't use as much' I'll listen to them, it's not really in their interest to have you cut down, so why would they say that?
just use half as much and half ibuprofen or something else
or go and see a doctor for the long term problem
the potential downside is very, very bad
the upside of using an extra gram of painkiller, not so much
many people are using it without toxicity, sure, that doesn't mean it's not a risk - and not many are using the maximum dose day-in day-out with harm, if any at all
If a manufacturer says 'don't use as much' I'll listen to them, it's not really in their interest to have you cut down, so why would they say that?
just use half as much and half ibuprofen or something else
or go and see a doctor for the long term problem
the potential downside is very, very bad
the upside of using an extra gram of painkiller, not so much
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