How much naproxen is okay?
Discussion
Teddy Lop said:
Took 2 500mg this morning as the gout flared up and 2 hours later having no effect.
Obviously if it persists or the naproxen fails to work generally I'll see a doc but to get me through my busy shedule what's the max a 40 yr old healthy male should use?
Sorry, cannot help, but do you take anything to prevent the build up of the euric crystals?Obviously if it persists or the naproxen fails to work generally I'll see a doc but to get me through my busy shedule what's the max a 40 yr old healthy male should use?
Sorry to say but you are close to the maximum recommended dose already. Standard for acute gout would be 750mg as a first dose then 250mg eight hours later and every eight hours until settled. In the UK we tend to suggest a maximum of 1g of Naproxen per 24 hrs ( other countries will allow up to 1.5g for a few days). If you are using for a few days remember to look after your stomach and if you are prone to heartburn getting some ranitidine might be prudent. Keep a decent fluid intake up (2-3 litres of water per day) to help protect your kidneys from the naproxen and flush some urate. If stuck get to the GP and discuss Colchicine as an additional or alternative treatment. Hope it settles quickly and if this is recurrent worth thinking about urate lowering therapy (allopurinol or febuxostat) to start 6 weeks after this episode settles.
Teddy Lop said:
TheAngryDog said:
Sorry, cannot help, but do you take anything to prevent the build up of the euric crystals?
No, TBF I've not had it in over a year, one or two is-it maybes but not proper. After best part of 4 hours the drugs have kicked in so okay now.I have Rheumatoid Arthritis, and I was diagnosed Naproxen in the early days when nothing touched it. At first I was given instructions to take 500mg twice a day but was upped to 1000mg twice a day but only for a short period of time. I was in so much pain that I took this PLUS 8 x Co-Codamol PLUS 8 x Tramadol. In one day 
What I did find was that it worked better if I took it before bed if I noticed a flare up coming, I was in less pain the next day. If I took it for pain management day-to-day then it was not effective.
I now live very comfortably with a single weekly injection and take barely any analgesics.
What I did find was that it worked better if I took it before bed if I noticed a flare up coming, I was in less pain the next day. If I took it for pain management day-to-day then it was not effective.
I now live very comfortably with a single weekly injection and take barely any analgesics.
technodup said:
If he's anything like me he'll have the 'pens' which you do yourself.
Yeh, the click pens. £10k a year it costs (Enbrel) but I've recently gone on the cheaper, generic alternative now that the patent has expired. I seem to be doing ok after 6 months of them and saving the NHS loads as well!They turned my life around. I'd struggle to climb stairs, had knuckles removed in one of my feet due to them fusing at 40years of age. It was only going one way until I had the injections.
Now work FT and play badminton etc.
The dosing rate is 10mg/kg twice a day (850mg twice a day for an 85kg man).
Take it with food and think about taking a proton pump inhibitor at the same time (20mg omeprazole once a day) to protect your stomach. Nexium over the counter if you're feeling rich or a script for generic omeprazole.
Take it with food and think about taking a proton pump inhibitor at the same time (20mg omeprazole once a day) to protect your stomach. Nexium over the counter if you're feeling rich or a script for generic omeprazole.
of an illness but I'm well aware there's plenty worse out there.Fastchas said:
Yeh, the click pens. £10k a year it costs (Enbrel) but I've recently gone on the cheaper, generic alternative now that the patent has expired. I seem to be doing ok after 6 months of them and saving the NHS loads as well!
They turned my life around. I'd struggle to climb stairs, had knuckles removed in one of my feet due to them fusing at 40years of age. It was only going one way until I had the injections.
Now work FT and play badminton etc.
There should be neglible difference between Enbrel and the biosimilar alternatives (either Erelzi or Benapali), the main difference being the excipients could differ but the efficacy is within 1-2% of Enbrel. RA patients seem to have switched and had no real problems but other patients who have gastro or dermatological conditions have suffered some adverse eventsThey turned my life around. I'd struggle to climb stairs, had knuckles removed in one of my feet due to them fusing at 40years of age. It was only going one way until I had the injections.
Now work FT and play badminton etc.
drdc1971 said:
Sorry to say but you are close to the maximum recommended dose already. Standard for acute gout would be 750mg as a first dose then 250mg eight hours later and every eight hours until settled. In the UK we tend to suggest a maximum of 1g of Naproxen per 24 hrs ( other countries will allow up to 1.5g for a few days). If you are using for a few days remember to look after your stomach and if you are prone to heartburn getting some ranitidine might be prudent. Keep a decent fluid intake up (2-3 litres of water per day) to help protect your kidneys from the naproxen and flush some urate. If stuck get to the GP and discuss Colchicine as an additional or alternative treatment. Hope it settles quickly and if this is recurrent worth thinking about urate lowering therapy (allopurinol or febuxostat) to start 6 weeks after this episode settles.
This is the definitive answer. /thread
Naproxen will screw your stomach up if you’re not taking protection in the form of omeprozole or similar. So don’t keep at that stuff as you’ll be taking other meds because of the damage you’re doing.
Get your uric acid checked, preferably first thing in the morning before any food. I had gout last summer. It was after a weekend session of rich food and alcohol. I did a dry November and got my UA tested after 3 weeks of dry. Is was 430, when it needed to be below 300! So the alcohol must have been pushing it a load higher. I’m now on 200mg of allopurinol a day to control my UA. I’ve also cut alcohol intake substantially (though not this week
). UA is now below 300, so under control.
I’m a couple of stone overweight, which also doesn’t help, so the new year need to see a lifestyle change as I love my food too much.
Get your uric acid checked, preferably first thing in the morning before any food. I had gout last summer. It was after a weekend session of rich food and alcohol. I did a dry November and got my UA tested after 3 weeks of dry. Is was 430, when it needed to be below 300! So the alcohol must have been pushing it a load higher. I’m now on 200mg of allopurinol a day to control my UA. I’ve also cut alcohol intake substantially (though not this week
). UA is now below 300, so under control. I’m a couple of stone overweight, which also doesn’t help, so the new year need to see a lifestyle change as I love my food too much.
I've recently joined the gout club with what were at first very small episodes first thing in the morning over the last few months, generally just a stiffness in my toes which would clear up within a few hours.
This was until last week when it didn't clear up as usual and progressively got worse.On Monday morning the doc' diagnosed gout, prescribed a course of Colchicine and sent me for a blood test.
Things are very much better now so just waiting to hear about the blood test results and trying to identify what caused it. The only change in my diet which has coincided with the attacks is an increase in Quorn products as I try to cut back my meat intake. My last blood test also showed my cholesterol was at the high end of healthy so I've started taking benecol yoghurt drinks to bring that down so I guess either one of those could be the culprit.
This was until last week when it didn't clear up as usual and progressively got worse.On Monday morning the doc' diagnosed gout, prescribed a course of Colchicine and sent me for a blood test.
Things are very much better now so just waiting to hear about the blood test results and trying to identify what caused it. The only change in my diet which has coincided with the attacks is an increase in Quorn products as I try to cut back my meat intake. My last blood test also showed my cholesterol was at the high end of healthy so I've started taking benecol yoghurt drinks to bring that down so I guess either one of those could be the culprit.
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