Conavirus - randomised control trial on vitamin D
Conavirus - randomised control trial on vitamin D
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irc

Original Poster:

9,412 posts

160 months

Sunday 27th September 2020
quotequote all
Apologies for yet another Covid thread but I thought this perhaps needed a new topic so it wasn't lost in the noise.

I have been taking a vit D supplement since the spring on the basis that it was likely to be helpful and would not do any harm if it had no effect. I was convinced by this article back in April.

https://drmalcolmkendrick.org/2020/04/28/covid-upd...

There has now been a randomised control trial on vitamin D with good results.

"The world’s first randomised control trial on vitamin D and Covid has just been published. The results are clear-cut. The trial, which took place in Spain at the Reina Sofía University Hospital, involved 76 patients suffering from Covid-19. Fifty of those patients were given vitamin D. The remaining 26 were not. Half of those not given Vitamin D became so sick that they needed to be put on intensive care. By comparison, only one person who was given Vitamin D requiring ICU admission.

Put another way, the use of Vitamin D reduced a patient’s risk of needing intensive care 25-fold. Two patients who did not receive Vitamin D died. And while the sample is too small to conclude that Vitamin D abolishes the risk of death in Covid patients, it is nonetheless an astonishing result"


https://www.telegraph.co.uk/news/2020/09/26/correc...

poo at Paul's

14,558 posts

199 months

Sunday 27th September 2020
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We have been taking it since Feb!

Like you, can’t do any harm.

Liokault

2,837 posts

238 months

Sunday 27th September 2020
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I have been on Vit D for a while...basically because Joe Rogan said to. I am taking much less than him though.

PorkInsider

6,382 posts

165 months

Sunday 27th September 2020
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Very interesting.

It sounds promising and, as said, no harm in starting taking vit D supplements in advance of any official advice.

MaxFromage

2,597 posts

155 months

Sunday 27th September 2020
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NHS already advise taking Vitamin D:

https://www.nhs.uk/conditions/vitamins-and-mineral...

anonymous-user

78 months

Sunday 27th September 2020
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There was a recent study, Vitamin D can half risk of fatal coronavirus complications.

https://www.independent.co.uk/news/health/coronavi...

''The study, published in the journal PLOS ONE, found patients older than 40 who had sufficient levels of vitamin D were more than 51 per cent less likely to die from the virus.''


Drew106

1,652 posts

169 months

Sunday 27th September 2020
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Living in the UK, supplementing Vit D is always a good idea.

anonymous-user

78 months

Sunday 27th September 2020
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A cynic would say that this is the better option but no one can really profit off it.

Teddy Lop

8,301 posts

91 months

Sunday 27th September 2020
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The Spruce Goose said:
A cynic would say that this is the better option but no one can really profit off it.
that's about the sum of it

anonymous-user

78 months

Sunday 27th September 2020
quotequote all
Teddy Lop said:
that's about the sum of it
it seems that the approach is negative enforcement, tell us what we can't do. What happens if they said, do excercise, take vit d, eat healthy etc

High doses of Vit c have worked for severe cases but funnily enough it isn't approved as a standard treatment for SARS-CoV-2.

''More recent research suggests that vitamin C also prevents the production of pro-inflammatory cytokines, including interleukin-6, a component of the cytokine release syndrome associated with severe COVID-19 that results in lung injury and leads to ARDS.''

https://www.medpagetoday.com/casestudies/infectiou...

Edited by anonymous-user on Sunday 27th September 23:25

Catz

4,852 posts

235 months

Sunday 27th September 2020
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Blood tests for something else last year meant I got an additional blood test for Vit D. Despite my sun loving ways and spending lots of time outdoors by late Nov I basically had zero Vit D in me.

I got a prescription for cholecalciferol (Vit D3) which sorted out all of the wonky blood results eventually.

My worry is that my prescription has now run out. I’ll be going to the pharmacist to see if I can buy the same obviously. You can only get one test a year for Vit D deficiency, no idea why this is, so just hope I can monitor my Vit D by myself.

I’ve read a fair bit about the importance of Vit D against coronavirus and I do believe what I’ve read. I’d advise everyone to take some supplements this year ... just hold off till I get my supplies in! smile

rxe

6,700 posts

127 months

Monday 28th September 2020
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I’ve been relying on being outside....

It does illustrate the utter clusterfk we are working under. We’ve had a glorious summer where the vast majority of the population need only step outside to make sufficient Vitamin D. But they’re tried to suppress the damn virus so that we all catch it in winter when Vit D levels are lower, Supplements it is then...

irc

Original Poster:

9,412 posts

160 months

Monday 28th September 2020
quotequote all
Ironic that the part of the population who probably get least natural vit D from sunlight, even in summer, are care home residents living behind locked doors who rarely get outside. Not the reason for the high death rates in care homes but perhaps a factor.

And excessive police zeal in a few places in enforcing the spring lockdown won't have helped either.


Teddy Lop

8,301 posts

91 months

Monday 28th September 2020
quotequote all
rxe said:
I’ve been relying on being outside....

It does illustrate the utter clusterfk we are working under. We’ve had a glorious summer where the vast majority of the population need only step outside to make sufficient Vitamin D. But they’re tried to suppress the damn virus so that we all catch it in winter when Vit D levels are lower, Supplements it is then...


there has been so much monumental ignorance about this, about all we know about viruses and viral transfer from the outset that's simply unfathomable.

PorkInsider

6,382 posts

165 months

Monday 28th September 2020
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irc said:
Ironic that the part of the population who probably get least natural vit D from sunlight, even in summer, are care home residents living behind locked doors who rarely get outside. Not the reason for the high death rates in care homes but perhaps a factor.
Also points to a possible reason that black people are disproportionately affected by the virus, or is that just too obvious???

rxe

6,700 posts

127 months

Monday 28th September 2020
quotequote all
PorkInsider said:
Also points to a possible reason that black people are disproportionately affected by the virus, or is that just too obvious???
Deaths in countries close to the equator seem to be low per head of population - especially when you consider the state of most of their health systems. Africa basically doesn’t seem to be affected, and India has a lot of cases, but the death rate per million is about 1/10th that of the US. The glaring exception seems to be Brazil.

andy43

12,631 posts

278 months

Monday 28th September 2020
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As already said positive reinforcement of some sort usually works better than telling people what they CAN'T do.
Advising Vit D supplement nationwide is a no brainer - and you've no idea you have low natural levels without a bloodtest.
UK winter/covid pandemic - take vit D. Get covid - take vit C. It's been written about for months.
We have been taking multivitamin tabs including vit D since all this started.

From what I've read there are few covid/D studies because Vit D is so cheap there's no appetite for investing in researching it.
Whether the higher incidence of BAME deaths could be due to known limited natural absorption I have no idea - same goes for the less mobile care home residents never feeling sun on their faces - but a worldwide push to take vit D would seem a sensible idea.

JagLover

46,201 posts

259 months

Monday 28th September 2020
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rxe said:
I’ve been relying on being outside....

It does illustrate the utter clusterfk we are working under. We’ve had a glorious summer where the vast majority of the population need only step outside to make sufficient Vitamin D. But they’re tried to suppress the damn virus so that we all catch it in winter when Vit D levels are lower, Supplements it is then...
Yep

Lockdown measures will very likely cost more lives than they save. Firstly through the impact on other medical treatments and secondly because we had lockdown measures in place throughout the summer months when that would have been a great time to catch it for most.

JagLover

46,201 posts

259 months

Monday 28th September 2020
quotequote all
andy43 said:
Whether the higher incidence of BAME deaths could be due to known limited natural absorption I have no idea - same goes for the less mobile care home residents never feeling sun on their faces - but a worldwide push to take vit D would seem a sensible idea.
It varies by community and there are also cultural factors.

South Asian women have some of the lowest levels. Dangerously low levels of Vitamin D are common among them.

SS2.

14,687 posts

262 months

Monday 28th September 2020
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My cousin is a sister on an dedicated (and extremely quiet) CV19 ward - for months, she's been stressing the importance of Vitamin D supplements.