Coronavirus - Is this the killer flu that will wipe us out?

Coronavirus - Is this the killer flu that will wipe us out?

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isaldiri

18,607 posts

169 months

Thursday 27th February 2020
quotequote all
Foliage said:
I think a lot of people miss the point about this virus, no medication, I repeat NO medication works against this virus, going to the doctors wont help at all, you have to ride it out in isolation and let your immune system deal with it NOTHING helps, not even paracetamol will help, its just wont bring the fever down. You have to ride it out
And where exactly have you found that out to make the claim absolutely no medicine of any sort works and even those that help control symptoms are ineffective.....?

Gareth79

7,687 posts

247 months

Thursday 27th February 2020
quotequote all
benji90 said:
mikal83 said:
If the FCO puts Gran Canaria off limits, your insurance policy is void...........no matter when you take it out.Thats my point.
No it really isn’t. Cancellation cover will only apply to holidays you book after you take out the insurance policy.

Insurers will cover your cancellation costs should the FCO advise against all but essential travel to your chosen destination.

Your policy will likely be void if you choose to travel if it is AGAINST the advise of the FCO.
I have standard Virgin Money insurance and the policy wording doesn't exclude cover for travel to an FCO advised area *so long as the trip was booked and the policy purchased before the advisory was issued*.

Likewise your statement about cancellation is incorrect for mine (and most will probably be similar) "Cover for cancellation starts from the date you book your trip or pay the insurance premium, whichever is the later, unless you have bought an annual multi-trip policy in which case cover for cancellation starts at the time you book your trip or the start date shown on your validation certificate, whichever is the later."

Dan_1981

17,404 posts

200 months

Thursday 27th February 2020
quotequote all
Been at Vienna airport for the last three hours with the usual footfall of people.

I've seen three people wearing masks in total.

Zero other activities / measures etc in the areas I've been - main terminal / check in / departures

No mention of Corona anywhere, no signs up etc.

nffcforever

793 posts

192 months

Thursday 27th February 2020
quotequote all
V6 Pushfit said:
I get the point but how do we get the % to 1%? Without going through it all again the rate is higher ....
A previous post of mine from a few days ago included links to 3 separate studies where the IFR was estimated by experts to be:

1. 0.5% - 0.8%
2. 0.94%
3. 1%

They are referenced by the WHO in Sit Rep 30.

anonymous-user

Original Poster:

55 months

Thursday 27th February 2020
quotequote all
nffcforever said:
A previous post of mine from a few days ago included links to 3 separate studies where the IFR was estimated by experts to be:

1. 0.5% - 0.8%
2. 0.94%
3. 1%

They are referenced by the WHO in Sit Rep 30.
Using case numbers or not?

Gregmitchell

1,745 posts

118 months

Thursday 27th February 2020
quotequote all
Shut FTSE down 4%!

anonymous-user

Original Poster:

55 months

Thursday 27th February 2020
quotequote all
We've seen the Chinese efforts at disinfecting the streets previously on this thread

Here is what a tweeter claims is the equivalent operation in an Iranian town

https://twitter.com/RuralCdn/status/12324732438580...

eldar

21,800 posts

197 months

Thursday 27th February 2020
quotequote all
p1stonhead said:
SARS and swine flu were supposed to do all this ste too.

Never happened.
Swine flu killed 575,000 people 11 years ago.

Foliage

3,861 posts

123 months

Thursday 27th February 2020
quotequote all
isaldiri said:
Foliage said:
I think a lot of people miss the point about this virus, no medication, I repeat NO medication works against this virus, going to the doctors wont help at all, you have to ride it out in isolation and let your immune system deal with it NOTHING helps, not even paracetamol will help, its just wont bring the fever down. You have to ride it out
And where exactly have you found that out to make the claim absolutely no medicine of any sort works and even those that help control symptoms are ineffective.....?
Where does it say it does? Have you read the WHO, CDC and NHS websites?


"Is there a vaccine, drug or treatment for COVID-19?
Not yet. To date, there is no vaccine and no specific antiviral medicine to prevent or treat COVID-2019. However, those affected should receive care to relieve symptoms. People with serious illness should be hospitalized. Most patients recover thanks to supportive care."

https://www.who.int/news-room/q-a-detail/q-a-coron...

"Treatment for coronavirus

There is currently no specific treatment for coronavirus.

Antibiotics do not help, as they do not work against viruses.

Treatment aims to relieve the symptoms while your body fights the illness.

You'll need to stay in isolation away from other people until you've recovered."

https://www.nhs.uk/conditions/coronavirus-covid-19...



anonymous-user

Original Poster:

55 months

Thursday 27th February 2020
quotequote all
JPJPJP said:
We've seen the Chinese efforts at disinfecting the streets previously on this thread

Here is what a tweeter claims is the equivalent operation in an Iranian town

https://twitter.com/RuralCdn/status/12324732438580...
Maybe its neat petrol, theyve got enough of it.

Graveworm

8,499 posts

72 months

Thursday 27th February 2020
quotequote all
superkartracer said:
Graveworm said:
Ccontingencies
Nonsense and pointless responding in any depth to such delusion.

nffcforever

793 posts

192 months

Thursday 27th February 2020
quotequote all
V6 Pushfit said:
nffcforever said:
A previous post of mine from a few days ago included links to 3 separate studies where the IFR was estimated by experts to be:

1. 0.5% - 0.8%
2. 0.94%
3. 1%

They are referenced by the WHO in Sit Rep 30.
Using case numbers or not?
Probably best to check the sources directly:

10 Jung S, Akhmetzhanov A, Hayashi K , Linton N, Yang Y , Yuan B, et al. Real-Time Estimation of the Risk of Death from Novel Coronavirus (COVID-19) Infection:
Inference Using Exported Cases, J. Clin. Med. 2020, 9(2), 523

https://www.mdpi.com/2077-0383/9/2/523

11 Dorigatti I, Okell L, Cori A, Imai N, Baguelin M, Bhatia S, et al. Report 4: Severity of 2019-novel coronavirus (nCoV),

https://www.imperial.ac.uk/mrc-globalinfectious-di...

12 Famulare M. 2019-nCoV: preliminary estimates of the confirmed-case-fatality-ratio and infection-fatality-ratio, and initial pandemic risk assessment,

https://institutefordiseasemodeling.github.io/nCoV...

isaldiri

18,607 posts

169 months

Thursday 27th February 2020
quotequote all
Foliage said:
However, those affected should receive care to relieve symptoms. People with serious illness should be hospitalized. Most patients recover thanks to supportive care."
According to you a few posts earlier nothing works. What is supportive care other than medication to stabilise symptoms....? It's probably not just a NHS nurse holding the patients hand.

superlightr

12,856 posts

264 months

Thursday 27th February 2020
quotequote all
Dan_1981 said:
Been at Vienna airport for the last three hours with the usual footfall of people.

I've seen three people wearing masks in total.

Zero other activities / measures etc in the areas I've been - main terminal / check in / departures

No mention of Corona anywhere, no signs up etc.
I think take your own normal precautions -wash hands often, don't eat at the airport, try not to touch your face with hands.

p_k_n

185 posts

92 months

Thursday 27th February 2020
quotequote all
Gregmitchell said:
Shut FTSE down 4%!
It's now below what it was at this time last year!

RizzoTheRat

25,192 posts

193 months

Thursday 27th February 2020
quotequote all
Foliage said:
isaldiri said:
Foliage said:
I think a lot of people miss the point about this virus, no medication, I repeat NO medication works against this virus, going to the doctors wont help at all, you have to ride it out in isolation and let your immune system deal with it NOTHING helps, not even paracetamol will help, its just wont bring the fever down. You have to ride it out
And where exactly have you found that out to make the claim absolutely no medicine of any sort works and even those that help control symptoms are ineffective.....?
Where does it say it does? Have you read the WHO, CDC and NHS websites?


"Is there a vaccine, drug or treatment for COVID-19?
Not yet. To date, there is no vaccine and no specific antiviral medicine to prevent or treat COVID-2019. However, those affected should receive care to relieve symptoms. People with serious illness should be hospitalized. Most patients recover thanks to supportive care."

https://www.who.int/news-room/q-a-detail/q-a-coron...

"Treatment for coronavirus

There is currently no specific treatment for coronavirus.

Antibiotics do not help, as they do not work against viruses.

Treatment aims to relieve the symptoms while your body fights the illness.

You'll need to stay in isolation away from other people until you've recovered."

https://www.nhs.uk/conditions/coronavirus-covid-19...
So exactly the same as for season flu then?

anonymous-user

Original Poster:

55 months

Thursday 27th February 2020
quotequote all
Reading that an Iranian cleric of some note Hadi Khasrushahi has died of Covid

knk

1,269 posts

272 months

Thursday 27th February 2020
quotequote all
This is a really sensible and factual summary on Covid-19 from doctorsnet.

Covid-19 “updated opinion”… ‘coz you haven’t had enough of it already! 7
By David Garner

What have we learned so far about Covid-19?

It spreads pretty well; each person infected and not isolated tends to infect another 2-3 people which can lead to an exponential growth in number of cases (currently over 80,000)
The incubation period is an average of about 5-6 days
The mortality outside of China is <1% (if you discount Iran which heavily skews the data with 15 deaths from only 95 cases)
If you put 3000 people in a closed environment with Covid-19 (Diamond Princess cruise ship) 695 people (23%) will get Covid-19
The World is putting a huge amount of effort into isolating areas with Covid-19 including Hubei province and yesterday Northern Italy

So how do we interpret what we have found out about Covid-19?

It spreads quickly and easily from person-to-person if we don’t employ the basic hygienic measure of strict hand hygiene, cough etiquette (use a tissue and wash your hands) and don’t mix with healthy people if you are unwell
The health impact of this infection on the majority of people is that it causes a mild infection a bit like the common cold or mild influenza; however if you are frail and already in poor health then the infection can be more severe (just as with influenza)
It is unlikely (and never was likely) that the measures taken by the global community will prevent the spread of Covid-19 around the World

What don’t we know about Covid-19?

The true mortality; at the beginning of an outbreak mortality data is skewed to severe cases with a higher mortality as only the sickest present to healthcare settings and get tested, the true mortality will be less than this
What is going on in countries with poor surveillance systems such as Sub-Saharan Africa; if Covid-19 gets into areas of the World with poor healthcare infrastructures with populations who are malnourished the mortality in those countries will be much higher than for us in the developed World
How many people are dying FROM Covid-19 and how many are dying WITH Covid-19; some of the people dying with a positive test result may be dying for another reason e.g. heart attack, cancer, etc. in which Covid-19 didn’t kill them but their death skews the mortality data

What is the impact of all of the resource being put towards controlling Covid-19 on other areas of healthcare; could people be coming to harm because of the distraction and redirection of resource?

So let’s have a look at some of what we know about Covid-19 and see if we can use this to explain some of the public health measures being employed at the moment.

The current management of the Covid-19 outbreak is based upon:

Reduced exposure to potentially infected people by restricting movement of people to or within outbreak areas
Rapid detection of new cases based upon broad definitions for potential cases
Isolation of new cases to prevent further spread
Self-isolation of exposed people so that if they become infected they don’t infect others
Quarantining of people with high-risk exposure until they are outside of the incubation period
All of this is designed to try and limit and slow down the spread of Covid-19. I suspect that trying to contain Covid-19 is like trying to turn back the tide, however slowing its spread does have a value.

Okay, so what happens if we slow the spread down?

Not only will this move any potential outbreak into the spring and summer when there is supposedly less strain on the NHS (yeh, really! Does the NHS actually experience a time where there is “less strain”). However in spring and summer people are less likely to be inside spreading their viruses around. The main benefit of slowing down the spread of the infection is that the overall peak of infection is less, so the impact at any one time is also less.

Consider
1) that everybody with Covid-19 might infect 3 other people and
2) they become unwell in 5 days.
In my graph below (based on very crude and basic maths!) I have assumed that every infected patient infects 3 people who become symptomatic on day 5. These original patients and the new cases then infect 3 more people each, who again become symptomatic five days late (I’ve assumed at this 10 day mark the original patients are better). If we start with 100 patients and then follow this graph out to 1 month you can see that by this stage you will have over 400,000 infected patients to deal with!

What happens if we manage to reduce the number of new infections to 2 new patients per patient with a 5 day incubation period (by isolating and using PPE)?
At 1 month this will reduce the number of cases to 73,000 patients. But if we manage to increase the incubation period to 7 days rather than 5 days (by delaying transmission by 2 days e.g. isolation and PPE), at 1 month we only have about 26,000 cases. These precautions slow Covid-19 down and this is why we have control measures in place at present.

Effects of Altering Covid-19's Incubation & Reproductive Rate on No. of Cases

In fact the number of people infected by a patient is known as the Reproductive Rate (RR). An RR of 2 means each infected person infects 2 other people, an RR of 15 means each infected person infects 15 other people. This number is important in outbreaks because if you can bring the RR below 1 then the outbreak is unable to sustain itself and burns out.

So this is the crux of all of the public health measures being taken globally. They are trying to get the Reproductive Rate to less than 1, so the outbreak burns out, whilst reducing the speed of spread so that the overall impact at any one time is minimised.

So if Covid-19 isn’t that bad why all the fuss?

Okay, some people are going to come to harm from Covid-19. The frail and the immunosuppressed and others with lots of comorbidities are at risk of serious infection with Covid-19. But that’s the case from all respiratory viruses such as influenza, Respiratory Syncytial Virus, Adenovirus, etc., etc. all of which we see as many thousands of cases every year. Therefore Covid-19 is going to cause infection in some people, and will probably replace the cause of their mortality from one of the more common viruses.

I think the main issue around Covid-19, and the main reason for the current public health strategies around the World, is to reduce the impact on the economies of affected countries. I know that sounds very cynical (and I am a cynic!) but even if it’s not the major reason it is a very real issue.

Think about it. If 20% of the population get Covid-19 and either are off work sick themselves, or having to be off work to look after sick children, then the economic impact of that missing workforce will be enormous. Factor in the number of healthcare workers not able to work because they have acquired the infection (including outside of work as well as from patients) then you can start to see the scale of the problem with people being unable to work.

Just look at what is happening to industries dependent on Chinese manufacturing which has ground to a halt in the worst hit areas of China. The same thing will happen in any country with sustained and uncontrolled transmission of Covid-19… at least until a large proportion of the population has had it and become immune, at which time transmission will start to go down, the RR will drop below 1, and the outbreak will burn itself out…

The other big problem PHE are going to have is repositioning the message from “killer deadly virus” to “it’s just like any other common cold” when Covid-19 is widespread in the community; I think the PHE might need a marketing agency to change this message for them.

At the moment there is a huge amount of amazing work being done to try and contain the virus, which currently involves: wearing hazmat suits, face masks, repatriating infected Nationals, testing an enormous amount of foreign travellers and self-isolating school children who have been on half-term skiing trips!

Once the government are no longer trying to contain Covid-19 (their 4-part plan is – Contain, Delay, Research and Mitigate) people will come into contact with Covid-19, and most of the patients will be related to cases who aren’t even known about (e.g. can you remember who you actually caught your last sore throat from?). When we get to thousands of cases, and widespread transmission in the community, this is when there will be no value in using PPE to prevent transmission in the healthcare setting, infection will be happening outside the hospital, just like flu does. The PHE message is likely to be one of “treat like any other respiratory virus and don’t worry about all of the space suits!” However this is going to be hard for everyone (medical staff, patients and the general public) to grasp. It is not because the danger from the disease has changed; it is that there is no longer a purpose in wearing the PPE. This is different to a viral haemorrhagic fever like Ebola, where the PPE is there to protect the healthcare staff from dying because Ebola has such a high mortality even in fit and healthy individuals. Covid-19 is not really the media’s “killer deadly virus”; Covid-19 is and will be as bad as many of the other respiratory viruses, which do have an associated mortality rate, especially in vulnerable patient groups.

Currently for Covid-19 the actions are all about contain it or slow it down, however watch this space as the advice will change if/when “containment” fails, then it will be cope as best we can with the influx of respiratory illnesses using all our “spare capacity!” :-)

… and then when this is over, we can all get back to our normal jobs… at least until the next big thing in the world of “woohoo it’s a new… virus, bacteria, parasite, fungus”.

superkartracer

8,959 posts

223 months

Thursday 27th February 2020
quotequote all
Graveworm said:
superkartracer said:
Graveworm said:
Ccontingencies
Nonsense and pointless responding in any depth to such delusion.
https://www.theguardian.com/world/2020/feb/26/wuhan-nurses-plea-international-medics-help-fight-coronavirus

Uk contingencies etc

p1stonhead

25,576 posts

168 months

Thursday 27th February 2020
quotequote all
eldar said:
p1stonhead said:
SARS and swine flu were supposed to do all this ste too.

Never happened.
Swine flu killed 575,000 people 11 years ago.
That’s my point. fk all happened to how we lived our lives.
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