This isn't particularly clever or acerbic, but for whenever someone was being boring or irritating, I always enjoyed my work colleague saying 'on your marks, get set, fk off.'
On a project with an argumentative client who found fault with everything, this was wrong, that was wrong. In meetings, the senior project man on our side would hear him out and then say, "Is it wrong, or is it different?"
I was once told that I use words like some people use their fists, after saying “I can explain it to you, but I can’t understand it for you” to a hapless colleague in a meeting.